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Thursday, February 25, 2010

Cancer / Oncology News From Medical News Today

NICE Instructs NHS On New Drug For Advanced Soft Tissue SarcomaNew guidance published today (24 February) by the National Institute for Health and Clinical Excellence (NICE) will give a specific group of cancer patients access to a new drug on the NHS which could help extend their lives. The guidance recommends trabectedin (Yondelis) for the treatment of certain patients with advanced soft tissue sarcoma...Miami Symposium Honors Fidler For Metastasis ResearchIsaiah J. Fidler, D.V.M, Ph.D., a pioneer in understanding how cancer spreads to other organs and then taps its new environment to thrive and grow, has received the Lifetime Achievement Award from Nature Publishing at the 2010 Miami Winter Symposium - Targeting Cancer Invasion and Metastasis. Fidler, a professor in The University of Texas M. D...Cancer Research UK Launches Groundbreaking Research Centre At BartsA new cancer centre, launched today, puts London at the forefront of cancer research. The Barts Cancer Research UK Centre is the latest link in a unique chain of centres being launched around the country. The Centre has been formed though a partnership between Cancer Research UK, Queen Mary, University of London, and Barts & The London NHS Trust...Scientists Unlock Key To Tamoxifen Resistance - Cancer Research UKCancer Research UK funded scientists have discovered why some breast cancers are resistant to the commonly used drug tamoxifen, their findings are published in Cancer Research. Tamoxifen is given to most women for around five years after they are diagnosed with breast cancer to help prevent the disease from coming back...Arsenic Exposure Activates An Oncogenic Signaling Pathway; Leads To Increased Cancer RiskResearchers have found a new oncogenic signaling pathway by which the environmental toxin arsenic may lead to adverse health effects, including bladder cancer. These study results are published in Cancer Research, a journal of the American Association for Cancer Research...Bitter Melon Extract Attacks Breast Cancer CellsThe extract from a vegetable that is common in India and China shows promise in triggering a chain of events that kills breast cancer cells and prevents them from multiplying, a Saint Louis University researcher has found. Ratna Ray, Ph.D...Complications And Mortality After Radical Cystectomy For Bladder Transitional Cell - The relation between the complication rate and patient gender is controversial, and the literature data are quite ambiguous with a few published studies failing to show any clear significant difference [1, 2]...Researchers Find Oncogene Is Important In Pancreatic Cancer Growth And SpreadResearchers at the Mayo Clinic campus in Florida have found that PKC-iota (PKCι), an oncogene important in colon and lung cancers, is over-produced in pancreatic cancer and is linked to poor patient survival. They also found that genetically inhibiting PKCι in laboratory animals led to a significant decrease in pancreatic tumor growth and spread...New Round Of UREP Grants For WCMC-Q StudentsTwenty-eight WCMC-Q students have received grants totaling $280,000 in the latest, seventh, round of funding from the Undergraduate Research Experience Program (UREP) to conduct advanced research projects with faculty members...SIBLING Proteins May Predict Oral CancerThe presence of certain proteins in premalignant oral lesions may predict oral cancer development, Medical College of Georgia researchers said. SIBLINGs, or Small Integrin-Binding Ligand N-linked Glycoproteins, are a family of five proteins that help mineralize bone but can also spread cancer. SIBLINGs have been found in cancers including breast, lung, colon and prostate...Oral Cancer Study Shows Full Tumor GenomeMayo Clinic researchers along with collaborators from Life Technologies are reporting on the application of a new approach for sequencing RNA to study cancer tumors. Their findings from a proof-of-principle study on oral carcinomas appear in the current issue of PLoS One, the online science journal...Testicular Cancer Diagnosis By Non-Invasive MRIResearchers have found that non-invasive magnetic resonance imaging (MRI) is a good diagnostic tool for the evaluation and staging of testicular cancer and may improve patient care by sparing some men unnecessary surgery, according to a study in the March issue of the American Journal of Roentgenology ( III Study Of Avastin Plus Chemotherapy In Advanced Stomach Cancer Did Not Meet Primary EndpointGenentech, Inc., a wholly owned member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that a Phase III study (AVAGAST) did not meet its primary endpoint of showing Avastin® (bevacizumab) plus Xeloda® (capecitabine) or 5-FU and cisplatin chemotherapy extended the lives of people with inoperable or advanced stomach (gastric) cancer, compared to chemotherapy alone...Lilly, Merck, And Pfizer Join Forces To Accelerate Research And Improve Treatment Of Lung And Gastric Cancers In AsiaEli Lilly and Company, Merck (also known as Merck Sharp & Dohme (MSD) outside the USA and Canada), and Pfizer Inc. today announced the formation of the Asian Cancer Research Group, Inc., (ACRG), an independent, not-for-profit company established to accelerate research and ultimately improve treatment for patients affected with the most commonly-diagnosed cancers in Asia...Molecular Methods For Classifying Breast Cancer Patients Produce Inaccurate And Inconsistent Results, Says Leading UK ResearcherNew research suggests that methods recently developed for the molecular classification of breast cancer may be unsuitable for selecting patients for clinical trials...Research Identifies Mechanism That Makes Cells Become TumorousResearchers from the Peninsula Medical School in Plymouth (UK), the Memorial Sloan-Kettering Cancer Center in New York, Cornell University in New York, Weil Medical College in New York and the Center for Neural Tumour Research in Los Angeles, have for the first time identified a key mechanism that makes certain cells become tumorous in the brain...Clues Emerge About Origins Of Coronary Artery Disease From Uncharted Region Of Human GenomeScientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have learned how an interval of DNA in an unexplored region of the human genome increases the risk for coronary artery disease, the leading cause of death worldwide...Brain Tumor Recurrence In Mice Prevented By Blocking Blood Vessel FormationPatients with glioblastoma multiforme (GBM), an extremely aggressive brain tumor, have a very poor prognosis. Despite high dose radiotherapy, 75% of patients die within two years, usually as a result of tumor recurrence within the irradiation field...A New Model For The Treatment Of Liver Disease: A Mouse With A Human LiverHow do you study - and try to cure in the laboratory - an infection that only humans can get? A team led by Salk Institute researchers does it by generating a mouse with an almost completely human liver...New Treatment To Prevent Cancer Recurrence Shows Promise In Stanford StudyGlioblastoma is one of the most deadly human brain cancers. Radiation can temporarily shrink tumors, but they nearly always recur within weeks or months and few patients survive longer than two years after diagnosis...Should We Perform Orchidopexy For Cryptorchidism In Children With Severe Encephalopathy? - The study concerned children with severe encephalopathy (SE). Cryptorchidism in these children is frequent and is often secondary to a spastic cremaster muscle provoking secondary retraction of an otherwise normal testis, without associated testicular dysplasia...Cancer Institute Of New Jersey Strengthens Hospital NetworkEnhancing its collective strength in the area of oncology research in the state, The Cancer Institute of New Jersey (CINJ) has announced that Cooper University Hospital will be the fourth affiliate hospital within its Network to receive the prestigious Major Clinical Research Affiliate (MCRA) designation. CINJ is a Center of Excellence at UMDNJ-Robert Wood Johnson Medical School...UT Southwestern Program Tackles Difficult Head, Neck CancersWhen head and neck tumors from sinus tumors to acoustic neuromas attached to the hearing and balance nerve at the base of the skull are located in close proximity to such sensitive areas such as the brain and eyes, they are particularly dangerous due to possible brain injury, visionary risk or hearing loss...Diffusion Of A Soluble Protein Through A Sensory CiliumA team of researchers led by Peter Calvert (SUNY Upstate Medical University) has, for the first time, measured the diffusion coefficient of a protein in a primary cilium and in other major compartments of a highly polarized cell. The study appears in the March issue of the Journal of General Physiology ...Unpacking Condensins' Function In Embryonic Stem CellsRegulatory proteins common to all eukaryotic cells can have additional, unique functions in embryonic stem (ES) cells, according to a study in the February 22 issue of the Journal of Cell Biology...

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